
Why does PermaNet® 3.0 have an increased efficacy with pyrethroid-resistant malaria vectors?
The synergist increases the efficacy of the deltamethrin and works in two major ways: by enhancing the penetration of the deltamethrin into the insect1 and by inhibiting the metabolic enzymes the mosquito uses to sequester or break down this insecticide2.
References
1. Ahmad, M. et al (2006) Delayed cuticular penetration and enhanced metabolism of deltamethrin in pyrethroid-resistant strains of Helicoverpa armigera from China and Pakistan. Pest Manag. Sci. 62: 805 – 810.
2. Moores, G. et al. (2005). Use of 'temporal synergism' to overcome insecticide resistance. Outlooks on Pest Management 16(1): 7-9.
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Top FAQ for PermaNet® 3.0
- What is PermaNet® 3.0, and how is it different from other bed nets?
- What does the rise of resistance mean for all of the bed nets currently in use around the world?
- How does PermaNet® 3.0 perform with different types and combinations of resistance mechanism?
- Why is resistance an important public health issue?
- Why does PermaNet® 3.0 have an increased efficacy with pyrethroid-resistant malaria vectors?
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